Journal of Natural Products · 1994 · 128 citations · 0 references
PharmacyMedicinal ChemistryPharmacologyDrug DiscoverySynthetic Medicinal ChemistryAntibacterial AgentsAntibacterial PharmacologyBioactive Natural ProductsNatural Product Drug DiscoveryAntimicrobial MetabolitesAntimicrobial Natural ProductsBactericidal AgentsBioactive Plant CompoundsLong-chain AlkenonesSecondary Metabolites
Antibacterial activity of various secondary metabolites from plants against Propionibacterium acnes was tested. In addition, the study of combinations of compounds to enhance the total activity against this follicular bacterium was investigated. A series of long-chain alcohols was studied in great detail to gain new insights into the role of the hydrophobic alkyl groups in the activity.