Circulation Journal · 2011 · 27 citations · 29 references
MedicineCardiologyRadiologyClinical CardiologyDiagnostic ImagingDiagnostic RadiologyCardiac AnatomyCardiac ImagingCardiovascular AnatomyCardiovascular ImagingCoronary Artery DiseaseIschemic Heart DiseaseCardiac Computed TomographyCardiac Segmental AnatomyComputed Tomography Coronary AssessmentCoronary Artery Disease DetectionCoronary Ct AngiographyCoronary Lesion AssessmentMyocardial ArchitectureMyocardial Infarction Imaging
BACKGROUND: Recent development of multi-detector computed tomography (MDCT) has made the detection of myocardial bridge (MB) easier on the left anterior descending coronary artery (LAD). The LAD segment proximal to the MB is well known to be susceptible to atherosclerosis. Anatomical characteristics of MB on LAD in patients with myocardial infarction (MI) were examined by MDCT. METHODS AND RESULTS: Subjects were 43 MI patients who had MB in the LAD and comprised 2 groups: 14 with culprit lesions in the LAD proximal to MB (culprit group) and 29 without culprit lesions in the LAD (non-culprit group). MB length, MB thickness, and the distance from the orifice of left main trunk (LMT) to MB entrance were compared. Age and coronary risk factors showed no significant difference between the 2 groups. MB length (P=0.011), MB thickness (P=0.035), and index of the length multiplied by thickness of MB (P=0.031) were significantly greater in the culprit group. The distance from the orifice of the LMT to MB entrance was significantly shorter in the culprit group (P=0.006). CONCLUSIONS: Anatomical properties of MB, such as length and thickness of MB as well as MB location, are associated with the formation of culprit lesions of LAD proximal to MB in MI.
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Hemodynamic Shear Stress and Its Role in Atherosclerosis
Adel M. Malek · JAMA · 1999 · 3.6K citations
Stephen Schroeder, Andreas F. Kopp, Andreas Baumbach et al. · Journal of the American College of Cardiology · 2001 · 733 citations
Medicine, Cardiology, Radiology +17