American Journal of Respiratory and Critical Care Medicine · 2007 · 64 citations · 50 references
In this clinically relevant ovine model of septic shock, hypercapnia had similar effects to dobutamine on hemodynamic variables and lactic acidosis. Hypercapnia improved tissue oxygenation and reduced lung edema formation more than dobutamine administration.
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Hypercapnic acidosis and mortality in acute lung injury*
David A. Kregenow, Gordon D. Rubenfeld, Leonard D. Hudson et al. · Critical Care Medicine · 2005 · 264 citations