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Publication | Open Access

MAT2B-GIT1 interplay activates MEK1/ERK 1 and 2 to induce growth in human liver and colon cancer

DOIFull Paper Access

81

Citations

17

References

2013

Year

Hui Peng, Lily Dara, Tony W.H. Li, Yuhua Zheng, Heping Yang, Maria Lauda Tomasi, Ivan Tomasi, Pasquale Giordano, José M. Mato, Shelly C. Lu
Hepatology

Abstract

MAT2B and GIT1 form a scaffold, which recruits and activates MEK and ERK to promote growth and tumorigenesis. This novel MAT2B/GIT1 complex may provide a potential therapeutic gateway in human liver and colon cancer. (HEPATOLOGY 2012).

References

YearCitations

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