Concepedia

Decreased Atherosclerotic Lesion Formation in CX3CR1/Apolipoprotein E Double Knockout Mice

Christophe Combadière, Stéphane Potteaux, Ji‐Liang Gao, Bruno Esposito, Saveria Casanova, Eric J. Lee, Patrice Debré, Alain Tedgui, Philip M. Murphy, Ziad Mallat

Circulation · 2003 · 465 citations · 23 references

DOI

Abstract

The CX3CR1-CX3CL1 pathway seems to play a direct and critical role in monocyte recruitment and atherosclerotic lesion development in a mouse model of human atherosclerosis.

References

23

Analysis of Fractalkine Receptor CX<sub>3</sub>CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion

Steffen Jung, Júlio Aliberti, Petra Graemmel et al. · Molecular and Cellular Biology · 2000 · 2.6K citations · Full text

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A new class of membrane-bound chemokine with a CX3C motif

J. Fernando Bazán, Kevin B. Bacon, Gary Hardiman et al. · Nature · 1997 · 2K citations

, , +8

Decreased lesion formation in CCR2−/− mice reveals a role for chemokines in the initiation of atherosclerosis

Landin Boring, Jennifa Gosling, Michael D. Cleary et al. · Nature · 1998 · 2K citations

, , +13

Absence of Monocyte Chemoattractant Protein-1 Reduces Atherosclerosis in Low Density Lipoprotein Receptor–Deficient Mice

Long Gu, Yoshikatsu Okada, Steven K. Clinton et al. · Molecular Cell · 1998 · 1.6K citations · Full text

, , +9

Identification and Molecular Characterization of Fractalkine Receptor CX3CR1, which Mediates Both Leukocyte Migration and Adhesion

Toshio Imai, Kunio Hieshima, Christopher A. Haskell et al. · Cell · 1997 · 1.5K citations · Full text

, , +14