Protein kinase C-ε protects MCF-7 cells from TNF-mediated cell death by inhibiting Bax translocation

An endotoxin-induced serum factor that causes necrosis of tumors.

E A Carswell, Lloyd J. Old, Robert Kassel et al. · Proceedings of the National Academy of Sciences · 1975 · 4.5K citations · Full text

Veterinary Medicine, Immunology, Pathobiology +15

Cytotoxicity‐dependent APO‐1 (Fas/CD95)‐associated proteins form a death‐inducing signaling complex (DISC) with the receptor.

Frank Kischkel, Stefan Hellbardt, Iris Behrmann et al. · The EMBO Journal · 1995 · 2.1K citations · Full text

Life Sciences, Cell Biology, Immunology +13

Movement of Bax from the Cytosol to Mitochondria during Apoptosis

Keith G. Wolter, Yi‐Te Hsu, Carolyn L. Smith et al. · The Journal of Cell Biology · 1997 · 1.8K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro

Barry J. Sugarman, Bharat B. Aggarwal, Philip E. Hass et al. · Science · 1985 · 1.6K citations

Medicine, Cancer Biology, Oncology +8

Bid Induces the Oligomerization and Insertion of Bax into the Outer Mitochondrial Membrane

Robert Eskes, Solange Desagher, Bruno Antonsson et al. · Molecular and Cellular Biology · 2000 · 1.2K citations

Life Sciences, Cell Biology, Molecular Biology +9