Hydralazine-induced lupus: is there a toxic metabolic pathway?

HYDRALAZINE-INDUCED SYSTEMIC LUPUS ERYTHEMATOSUS: INFLUENCE OF HLA-DR AND SEX ON SUSCEPTIBILITY

J. R. Batchelor, K. I. Welsh, Roberto Tinoco et al. · The Lancet · 1980 · 385 citations

Rheumatology, Autoimmune Disease, Systemic Lupus Erythematosus Treatment +5

Relationship of acetyl transferase activity to antinuclear antibodies and toxic symptoms in hypertensive patients treated with hydralazine.

Perry Hm, Tan Em, Sharon E. Carmody et al. · PubMed · 1970 · 258 citations

An improved and simplified method of detecting the acetylator phenotype.

David A. Evans · Journal of Medical Genetics · 1969 · 238 citations · Full text

Molecular Pharmacology, Medicine, Genetics +9

SYNDROME SIMULATING COLLAGEN DISEASE CAUSED BY HYDRALAZINE (APRESOLINE)

H. Mitchell Perry · Journal of the American Medical Association · 1954 · 203 citations

Drug Safety, Medicinal Chemistry, Disease Mechanism +14

Acetylator Phenotype in Patients with Hydralazine‐induced Lupoid Syndrome

I. Strandberg, G Boman, Leo Hassler et al. · Acta Medica Scandinavica · 1976 · 102 citations