Cages Augmented With Mineralized Collagen and Platelet-Rich Plasma as an Osteoconductive/Inductive Combination for Interbody Fusion

Abstract

The MCM alone is not able to replace autologous bone grafts. Early activation of the platelets by calcium, which is released from mineralized collagen, could be the reason for the insufficient osteoinductive effect of PRP. In consequence, the combined application of mineralized collagen and PRP had no significant osteoinductive effect in this model.