6-Chloro-d,l-tryptophan, 4-chloro-3-hydroxyanthranilate and dexamethasone attenuate quinolinic acid accumulation in brain and blood following systemic immune activation

Quinolinic Acid: An Endogenous Metabolite That Produces Axon-Sparing Lesions in Rat Brain

Robert Schwarcz, William O. Whetsell, Richard M. Mangano · Science · 1983 · 1.3K citations

Life Sciences, Neurobiology, Neuroscience +16

Blood–Brain Barrier Transport of Kynurenines: Implications for Brain Synthesis and Metabolism

Shinsuke Fukui, Robert Schwarcz, Stanley I. Rapoport et al. · Journal of Neurochemistry · 1991 · 761 citations

Medicine, Neuroscience, Pharmacology +17

QUINOLINIC ACID AND KYNURENINE PATHWAY METABOLISM IN INFLAMMATORY AND NON-INFLAMMATORY NEUROLOGICAL DISEASE

Melvyn P. Heyes, Kuniaki Saito, Jeffrey S. Crowley et al. · Brain · 1992 · 684 citations

Life Sciences, Neuroscience, Pharmacology +14

Quinolinic acid in cerebrospinal fluid and serum in HIV‐1 Infection: Relationship to clinical and neurological status

Melvyn P. Heyes, Bruce J. Brew, Alex Martin et al. · Annals of Neurology · 1991 · 572 citations

Medicine, Infectious Diseases, Neurology +13

Tryptophan degradation in mice initiated by indoleamine 2,3-dioxygenase.

Osamu Takikawa, Ryotaro Yoshida, R. Kido et al. · Journal of Biological Chemistry · 1986 · 375 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14