In vivo establishment and characterization of a paclitaxel-resistant human ovarian cancer cell line showing enhanced growth properties and drug-resistance only in vivo

Cyclophosphamide and Cisplatin Compared with Paclitaxel and Cisplatin in Patients with Stage III and Stage IV Ovarian Cancer

William P. McGuire, William J. Hoskins, Mark F. Brady et al. · New England Journal of Medicine · 1996 · 2.9K citations · Full text

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A Combined Assay of Cell Viability and in Vitro Cytotoxicity with a Highly Water-Soluble Tetrazolium Salt, Neutral Red and Crystal Violet.

Munetaka Ishiyama, Hideyuki Tominaga, Masanobu Shiga et al. · Biological and Pharmaceutical Bulletin · 1996 · 733 citations · Full text

Pharmacy, Toxicology, Analytical Toxicology +12

Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes.

Maria Kavallaris, Dennis Yi‐Shin Kuo, Catherine A. Burkhart et al. · Journal of Clinical Investigation · 1997 · 599 citations · Full text

Medicine, Oncology, Pharmacology +17

Taxol binds to cellular microtubules.

James J. Manfredi, Jerome Parness, S. B. Horwitz · The Journal of Cell Biology · 1982 · 410 citations · Full text

Life Sciences, Cell Biology, Pharmacology +13

Tumor Resistance to Alkylating Agents Conferred by Mechanisms Operative Only in Vivo

Beverly A. Teicher, Terence S. Herman, Sylvia A. Holden et al. · Science · 1990 · 317 citations

Medicine, Oncology, Pharmacology +16