R-92L and R-92W Mutations in Cardiac Troponin T Lead to Distinct Energetic Phenotypes in Intact Mouse Hearts

Hypertrophic cardiomyopathy due to sarcomeric gene mutations is characterized by impaired energy metabolism irrespective of the degree of hypertrophy

Jenifer Crilley, Ernest Boehm, Edward Blair et al. · Journal of the American College of Cardiology · 2003 · 433 citations

Medicine, Cardiology, Genetics +12

Diastolic dysfunction and altered energetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy.

Matthias Spindler, Kurt W. Saupe, Michael E. Christe et al. · Journal of Clinical Investigation · 1998 · 269 citations · Full text

Life Sciences, Cardiology, Physiology +14

Impaired Cardiac Energetics in Mice Lacking Muscle-Specific Isoenzymes of Creatine Kinase

Kurt W. Saupe, Matthias Spindler, Rong Tian et al. · Circulation Research · 1998 · 183 citations · Full text

Life Sciences, Cardiology, Physiology +17

Disease-Causing Mutations in Cardiac Troponin T: Identification of a Critical Tropomyosin-Binding Region

Thomas Palm, Sarah Graboski, Sarah E. Hitchcock‐DeGregori et al. · Biophysical Journal · 2001 · 134 citations · Full text

Life Sciences, Genetics, Molecular Biology +8

Decreased energetics in murine hearts bearing the R92Q mutation in cardiac troponin T

Maryam M. Javadpour, Jil C. Tardiff, Ilka Pinz et al. · Journal of Clinical Investigation · 2003 · 124 citations · Full text

Life Sciences, Cardiology, Physiology +16