Pharmacokinetics and pharmacodynamics of tocilizumab after subcutaneous administration in patients with rheumatoid arthritis - Concepedia

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Pharmacokinetics and pharmacodynamics of tocilizumab after subcutaneous administration in patients with rheumatoid arthritis

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Citations

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References

2013

Year

Xiaoping Zhang, Ya‐Chi Chen, Scott Fettner, Lucy Rowell, Tatiana Gott, Paul Grimsey, Adam Unsworth

International Journal of Clinical Pharmacology and Therapeutics

Abstract

Greater tocilizumab exposure and sIL-6R elevation and more rapid CRP level normalization occurred with QW than with Q2W dosing. Both regimens demonstrated clinical benefit and were well tolerated.