Effects of Severe Hypocapnia on Expression of Bax and Bcl-2 Proteins, DNA Fragmentation, and Membrane Peroxidation Products in Cerebral Cortical Mitochondria of Newborn Piglets

Abstract

The data demonstrate that severe hypocapnia results in increased Bax expression, DNA fragmentation, and membrane lipid peroxidation in mitochondria of cerebral cortical neurons of newborn piglets, and may result in apoptotic cell death.