Silver‐Catalyzed Decarboxylative Acylarylation of Acrylamides with α‐Oxocarboxylic Acids in Aqueous Media

Abstract

Abstract A mild and efficient silver‐catalyzed acylarylation of activated alkenes with easily available α‐oxocarboxylic acids has been developed. The reactions provide a rapid access to a variety of functionalized oxindoles via a tandem decarboxylative radical cyclization strategy. This transformation proceeds well under mild reaction conditions and exhibits excellent functional group tolerance, affording the desired oxindoles in good to excellent yields. magnified image