Detection of specific alleles by using allele-specific primer extension followed by capture on solid support

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

Randall K. Saiki, Stephen J. Scharf, Fred Faloona et al. · Science · 1985 · 9K citations

Immunohematology, Genetic Testing, Genetics +20

Specific Enzymatic Amplification of DNA In Vitro: The Polymerase Chain Reaction

Kary B. Mullis, Fred Faloona, S. Scharf et al. · Cold Spring Harbor Symposia on Quantitative Biology · 1986 · 3.5K citations

Genetics, Dna Analysis, Molecular Biology +20

Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes

Randall K. Saiki, Teodorica L. Bugawan, Glenn T. Horn et al. · Nature · 1986 · 1.8K citations

Hla-dqα Dna, Allele-specific Oligonucleotide Probes, Biochemistry +12

A Ligase-Mediated Gene Detection Technique

Ulf Landegren, Robert Kaiser, Jane Z. Sanders et al. · Science · 1988 · 828 citations

Dna, Genetics, Dna Analysis +21

A primer-guided nucleotide incorporation assay in the genotyping of apolipoprotein E

Ann‐Christine Syvänen, Katriina Aalto‐Setälä, Leena Harju et al. · Genomics · 1990 · 390 citations

Apolipoprotein E, Biochemistry, Molecular Biological Method +6