Concepedia

The Use of a Tropism-Modified Measles Virus in Folate Receptor–Targeted Virotherapy of Ovarian Cancer

Kosei Hasegawa, Takafumi Nakamura, Mary Harvey, Yasuhiro Ikeda, Ann L. Oberg, Mariangela Figini, Silvana Canevari, Lynn C. Hartmann, Kah-Whye Peng

Clinical Cancer Research · 2006 · 83 citations · 37 references

DOIFull text

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Abstract

A FR-exclusive ovarian cancer targeted oncolytic virus was generated and shown to be therapeutically effective, thus introducing a new modality for FR targeting and a candidate measles virus for clinical testing.

References

37

Cancer Statistics, 2005

Ahmedin Jemal, Thomas S. Murray, Elizabeth Ward et al. · CA A Cancer Journal for Clinicians · 2005 · 5.5K citations · Full text

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Openings between Defective Endothelial Cells Explain Tumor Vessel Leakiness

Hiroya Hashizume, Shunichi Morikawa, John W. McLean et al. · American Journal Of Pathology · 2000 · 1.7K citations · Full text

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SLAM (CDw150) is a cellular receptor for measles virus

Hironobu Tatsuo, Nobuyuki Ono, Kotaro Tanaka et al. · Nature · 2000 · 1K citations

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The human CD46 molecule is a receptor for measles virus (Edmonston strain)

Ruth E. Dörig, Anne Marcil, Arvind Chopra et al. · Cell · 1993 · 1K citations

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Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues.

Steven Weitman, Richard H. Lark, Leslie R. Coney et al. · PubMed · 1992 · 1K citations

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