Counselling implications of chromosomal abnormalities other than trisomy 21 detected through a maternal serum screening programme

Abstract

Women undergoing maternal serum screening and, in particular, those proceeding to amniocentesis, should be informed that there is an equal chance that a chromosomal abnormality other than trisomy 21 will be found at amniocentesis, the nature of which usually requires parental samples and specialist counselling.