Annals of the New York Academy of Sciences · 2005 · 27 citations · 8 references
Life SciencesNeurologyNeuroscienceMotor ControlMovement AnalysisMovement DisordersCerebellar Control Of MovementCerebellar FunctionCerebellar Motor FunctionCerebellar PhysiologyNeurodegenerative DiseasesNeurodegenerative DisordersAtaxia SyndromesDisease DurationPolyglutamine DiseasesPolyglutamine Expansion DisordersSaccade LatencySaccadic Velocity MeasurementSpinocerebellar Ataxia Type 2Surrogate Screening
We measured in 82 spinocerebellar ataxia type 2 (SCA2) patients and in 80 controls maximal saccade velocity (MSV) and correlated it to polyglutamine expansion size and disease duration. MSV is strongly decreased in SCA2 patients and is influenced mostly by polyglutamine size.
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Spinocerebellar ataxia 2 (SCA2): morphometric analyses in 11 autopsies
R Estrada, J Galarraga, Guillermo Hernández Orozco et al. · Acta Neuropathologica · 1999 · 221 citations
Autosomal dominant cerebellar ataxia
G. Orozco Diaz, A. Nodarse Fleites, R. Cordovés Sagaz et al. · Neurology · 1990 · 168 citations
Medicine, Neurology, Neuroscience +17
Lüdger Schöls · Archives of Neurology · 1997 · 133 citations
Life Sciences, Genetics, Neurology +12