1-Aminocyclopropanecarboxylates exhibit antidepressant and anxiolytic actions in animal models

Behavioral despair in mice: a primary screening test for antidepressants.

Porsolt Rd, Aurélie Bertin, M Jalfre · PubMed · 1977 · 3.3K citations

Medicine, Pharmacology, Psychiatry +17

Glycine potentiates the NMDA response in cultured mouse brain neurons

John Johnson, Philippe Ascher · Nature · 1987 · 3.1K citations

Life Sciences, Neurobiology, Neuroscience +14

The use of a plus-maze to measure anxiety in the mouse

Richard G. Lister · Psychopharmacology · 1987 · 2.6K citations

Nursing, Behavioral Sciences, Psychology +6

Requirement for Glycine in Activation of NMDA-Receptors Expressed in <i>Xenopus</i> Oocytes

Nancy W. Kleckner, Raymond Dingledine · Science · 1988 · 1.4K citations

Life Sciences, Neurobiology, Neuroscience +17

Functional antagonists at the NMDA receptor complex exhibit antidepressant actions

Ramón Trullás, P. Skolnick · European Journal of Pharmacology · 1990 · 777 citations

Medicine, Neuroscience, Pharmacology +12