Specific interactions of monotetrahydrofuranic annonaceous acetogenins as inhibitors of mitochondrial complex I

Three Classes of Inhibitors Share a Common Binding Domain in Mitochondrial Complex I (NADH:Ubiquinone Oxidoreductase)

Jürgen G. Okun, Peter Lümmen, Ulrich Brandt · Journal of Biological Chemistry · 1999 · 307 citations · Full text

Two binding sites of inhibitors in NADH:ubiquinone oxidoreductase (complex I)

Thorsten Friedrich, Petra van Heek, Hans Leif et al. · European Journal of Biochemistry · 1994 · 250 citations · Full text

Inhibitory Activity, Biochemistry, Natural Sciences +11

Natural substances (acetogenins) from the family <i>Annonaceae</i> are powerful inhibitors of mitochondrial NADH dehydrogenase (Complex I)

Mauro Degli Esposti, Anna Ghelli, Marina Ratta et al. · Biochemical Journal · 1994 · 238 citations · Full text

Phytoalexin, Complex I. Rolliniastatin-1, Mitochondrial Function +14

Assay conditions for the mitochondrial NADH:coenzyme Q oxidoreductase

Ernesto Estornell, Romana Fato, Francesco Pallotti et al. · FEBS Letters · 1993 · 207 citations · Full text

Medicinal Chemistry, Homolog Coq1, Aldo-keto Reductase +14

Natural acetogenins from annonaceae, synthesis and mechanisms of action

M. Carmen Zafra‐Polo, Bruno Figadère, Teresa Gallardo et al. · Phytochemistry · 1998 · 191 citations

Biology, Biosynthesis, Bioorganic Chemistry +5