Reduction of recurrent HSV disease using imiquimod alone or combined with a glycoprotein vaccine

A Double-Blind Study of Oral Acyclovir for Suppression of Recurrences of Genital Herpes Simplex Virus Infection

John M. Douglas, Cathy W. Critchlow, Jacqueline Benedetti et al. · New England Journal of Medicine · 1984 · 341 citations

Oral Acyclovir, Viral Persistence, Placebo Recipients +15

Modulation of TH1 and TH2 Cytokine Production with the Immune Response Modifiers, R-848 and Imiquimod

Tamara L. Wagner, Cory L. Ahonen, Aimee M. Couture et al. · Cellular Immunology · 1999 · 261 citations

Inflammation, Cytokine, Allergy +10

Clinical Reactivation of Genital Herpes Simplex Virus Infection Decreases in Frequency over Time

Jacqueline Benedetti, Judith E. Zeh, Lawrence Corey · Annals of Internal Medicine · 1999 · 179 citations

Modification of immunological responses and clinical disease during topical R-837 treatment of genital HSV-2 infection

Christopher J. Harrison, Laura J. Jenski, T. Voychehovski et al. · Antiviral Research · 1988 · 154 citations

Viral Persistence, Antiviral Response, Vaginitis +8

Management of acyclovir-resistant herpes simplex and varicella-zoster virus infections.

Henry H. Balfour, Constance A. Benson, J. Braun et al. · PubMed · 1994 · 135 citations

Immunology, Antiviral Drug, Viral Persistence +16