Concepedia

Design, synthesis and evaluation of galanthamine derivatives as acetylcholinesterase inhibitors

Ping Jia, Rong Sheng, Jing Zhang, Liang Fang, Qiaojun He, Bo Yang, Yongzhou Hu

European Journal of Medicinal Chemistry · 2008 · 69 citations · 19 references

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Concepts

References

19

A new and rapid colorimetric determination of acetylcholinesterase activity

George L. Ellman, K. Diane Courtney, Valentino Andres et al. · Biochemical Pharmacology · 1961 · 26.9K citations

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Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

Garrett M. Morris, David S. Goodsell, Robert S. Halliday et al. · Journal of Computational Chemistry · 1998 · 10.8K citations

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β-Amyloid aggregation induced by human acetylcholinesterase: inhibition studies

Manuela Bartolini, Carlo Bertucci, Vanni Cavrini et al. · Biochemical Pharmacology · 2003 · 569 citations

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A Structural Motif of Acetylcholinesterase That Promotes Amyloid β-Peptide Fibril Formation

G. Ferrari, Mauricio Canales, Irina Shin et al. · Biochemistry · 2001 · 407 citations

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The Complex of a Bivalent Derivative of Galanthamine with <i>Torpedo</i> Acetylcholinesterase Displays Drastic Deformation of the Active-Site Gorge:  Implications for Structure-Based Drug Design

Harry M. Greenblatt, Catherine Guillou, Daniel Guénard et al. · Journal of the American Chemical Society · 2004 · 124 citations · Full text

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