Bulletin of the Korean Chemical Society · 2011 · 17 citations · 15 references
Natural SciencesBiochemistryChemistryChemical KineticsOrganic ChemistryChemical Reaction KineticsEnzyme KineticsKinetic Isotope Effect In Organic ReactionsSolvent Effects On Reaction MechanismsSolvent Effects On Reaction RatesSolvent Kinetic Isotope Effect
2 mechanism, Ki-netic solvent isotope effectChloroformate esters (ROCOCl, 1) are known to hydro-lyse much more slowly than other acyl chlorides (RCOCl).Initial-state stabilization through π-electron resonance (2)has been suggested to be responsible for the decreasedreactivity of 1, since such resonance interaction is notpossible for RCOCl.
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T. William Bentley, Gillian E. Carter · Journal of the American Chemical Society · 1982 · 230 citations