The Diagnosis of Legionnaires' Disease

Abstract

Editorials1 September 1978The Diagnosis of Legionnaires' DiseaseTHEODORE F. TSAI, M.D., DAVID W. FRASER, M.D., F.A.C.P.THEODORE F. TSAI, M.D.Search for more papers by this author, DAVID W. FRASER, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-89-3-413 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptLaboratory methods to confirm the diagnosis of Legionnaires' disease are becoming more widely used, and the disease is proving to be sufficiently common so that all physicians attending patients with pneumonia should be familiar with its features. Since August 1977 more than 100 cases have been documented in five outbreaks, including one outbreak in Wadsworth Veterans Administration Hospital; and in the last 2 years more than 270 sporadic cases have been confirmed. The report by Kirby and colleagues in this issue (p. 297) should assist clinicians in the appraisal of patients suspected of having the disease. We wish to add...References1. CHERRYPITTMANHARRISHEBERTTHOMASONTHACKERWEAVER WBPGBLR: Detection of Legionnaires' disease bacterium by direct immunofluorescent staining. J Clin Microbiol, in press Google Scholar2. FEELEYGORMANWEAVERMACKELSMITH JGRDH: Primary isolation media for The Legionnaires' disease bacterium. J Clin Microbiol, in press. Google Scholar3. MCDADESHEPARDFRASERTSAIREDUSDOWDLE JCDTMW: Legionnaires' disease. Isolation of a bacterium and demonstration of its role in other respiratory disease. N Engl J Med 297:1197-1203, 1977 CrossrefMedlineGoogle Scholar4. SCHWARTZGORRYKASSIRERESSIG WGJA: Decision analysis and clinical judgment. Am J Med 55:459-472, 1973 CrossrefMedlineGoogle Scholar5. FEINSTEIN A: Clinical Biostatistics. St. Louis, C. V. Mosby Co., 1977, pp. 214-226 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: THEODORE F. TSAI, M.D.; DAVID W. FRASER, M.D., F.A.C.P.Affiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMammalian Solute Carrier (SLC)-like transporters of Legionella pneumophilaInterferon-gamma (IFN-γ) production by human T lymphocytes upon Legionella pneumophila stimulation in vitroReplyLegionella and community-acquired pneumonia: a review of current diagnostic tests from a clinician’s viewpointLegionellosisSerological Cross-Reaction between Legionella pneumophila and Citrobacter freundii in Indirect Immunofluorescence and Rapid Microagglutination TestsOverwhelming pneumoniaProduction of Monoclonal Antibodies against Legionella pneumophila Serogroup 1Aerobic and Facultatively Anaerobic BacteriaLegionella and Legionnaires' Disease: A Review with Emphasis on Environmental Studies and Laboratory DiagnosisUnusual progression of a Legionella pneumophila infection in a young childPyridines and their Benzo Derivatives: (vi) ApplicationsVolume 2 ReferencesRapid Diagnosis of Legionnaires' Disease by Bronchoalveolar LavageSerological Tests for Legionella Pneumophila Serogroup 1 InfectionsEffects of alpha-amylase on in vitro growth of Legionella pneumophilaDisseminated Tuberculosis Caused by Mycobacterium intracellulare (Update)A rapid microagglutination test for the diagnosis of Legionella pneumophila (serogroup 1) infectionLaboratory Diagnosis of Infections Caused by Legionella SpeciesDisseminated Legionella pneumophila infection in an infant with severe combined immunodeficiencyConcurrent Antibody Rises to C psittaci and L pneumophila in a Patient with PsittacosisLegionellosisComparison of Specific Immunoglobulin G, M and Agglutinating Antibodies against Legionella PneumophilaContribution à l'étude de la nature des relations entre leptosporioses et légionellosesSeroreactivity to Mycoplasma pneumoniae and Legionella pneumophila: lack of a statistically significant relationshipDirect Immunofluorescence in the Diagnosis of Legionnaires' DiseaseLegionnaires' Disease in Leukaemic ReticuloendotheliosisDetection of antibodies to Legionella pneumophila in immune guinea pig serum by solid-phase immunofluorescenceAerobic and Facultatively Anaerobic BacteriaThe diagnosis of Legionnaires' disease by counterimmunoelectrophoresis.Prolonged Cavitating Pneumonia in a Patient with Serologic Evidence of Legionnaires' DiseaseMaladie des Légionnaires et Leptospiroses : parentés épidémiologiques ou antigéniques ?Legionnaires' disease serology: Effect of antigen preparation on specificity and sensitivity of the indirect fluorescent antibody testLegionnaires' Disease: Indirect Fluorescent Antibody Test in DiagnosisGARY L. LATTIMER, M.D.Legionellosis: Legionnaires’ disease; Pontiac feverThe Rickettsia-like Organisms TATLOCK (1943) and HEBA (1959): Bacteria Phenotypically Similar to but Genetically Distinct from Legionella pneumophila and the WIGA BacteriumG. ANN HÉBERT, B.S., C. WAYNE MOSS, Ph.D., LINDA KIRVEN McDOUGAL, M.S., F. MARILYN BOZEMAN, M.S., ROGER M. McKINNEY, Ph.D., DON J. BRENNER, Ph.D.Serology of Legionnaires disease: comparison of indirect fluorescent antibody, immune adherence hemagglutination, and indirect hemagglutination testsDiagnostic Specificity of Immunoglobulin M (IgM) Response in Differentiating Legionnaires' Disease from PsittacosisLegionnaires' disease: case report with special emphasis on electron microscopy and potential risk of infection at autopsyCorrection: Locations of Legionnaires' Disease ClustersTHEODORE F. TSAI, M.D., DAVID W. FRASER, M.D., CHARLES M. HELMS, M.D., PH.D., JOHN P. VINER, M.D., WALTER J. HIERHOLZER JR., M.D., ROBERT J. CORRY, M.D., EDWARD D. RENNER, PH.D., LAVERNE A. WINTERMEYER, M.D.Plague and TularemiaClinical Aspects of Legionnaires' DiseaseMORTON N. SWARTZ, M.D.The Philadelphia Epidemic of Legionnaire's Disease: Clinical, Pulmonary, and Serologic Findings Two Years LaterGARY L. LATTIMER, M.D., LUTHER V. RHODES III, M.D., JOHN S. SALVENTI, Ph.D., JOHN P. GALGON, M.D., VICTOR STONEBRAKER, SHARON BOLEY, B.S., GARY HAASEarly Clinical Differentiation Between Legionnaires' Disease and Other Sporadic PneumoniasANDREW C. MILLER, M.D., D. Phil.Comparative Features of Pneumococcal, Mycoplasmal, and Legionnaires' Disease PneumoniasCHARLES M. HELMS, M.D., Ph.D., JOHN P. VINER, M.D., RANDALL H. STURM, M.D., EDWARD D. RENNER, Ph.D., WILLIAM JOHNSON, Ph.D.Summertime Pneumonias in Philadelphia in 1976 An Epidemiologic StudyROBERT G. SHARRAR, M.D., HARVEY M. FRIEDMAN, M.D., WALLACE T. MILLER, M.D., MITCHELL J. YANAK, B.A., ELIAS ABRUTYN, M.D.Legionnaires' Disease in Pneumonia Patients in Iowa A Retrospective Seroepidemiologic Study, 1972-1977E. D. RENNER, Ph.D., C. M. HELMS, M.D., Ph.D., W. J. HIERHOLZER Jr., M.D., N. HALL, M.T., Y. W. WONG, M.S., J. P. VINER, M.D., W. JOHNSON, Ph.D., W. J. HAUSLER Jr., Ph.D.Direct In-Vitro Isolation of the Legionnaires' Disease Bacterium in Two Fatal Cases Cultural and Staining CharacteristicsMORRIS DUMOFF, Ph.D.Lessons from Legionnaires' DiseaseROBERT P. HUDSON, M.D.Legionnaires' Disease — The First Thousand DaysIndirect immunofluorescence test for serodiagnosis of Legionnaires disease: evidence for serogroup diversity of Legionnaires disease bacterial antigens and for multiple specificity of human antibodiesEASY VISUALISATION OF LEGIONELLA PNEUMOPHILA BY "HALF-A-GRAM" STAIN PROCEDURELEGIONELLA PNEUMOPHILA SEROTYPESLEGIONNAIRES' DISEASE AND CEREBRAL DISTURBANCEHIGH-TENSION ELECTRICAL INJURYDiagnosis of Legionnaires' Disease from Transtracheal Aspirate by Direct Fluorescent-Antibody Staining and Isolation of the Bacterium 1 September 1978Volume 89, Issue 3Page: 413-414KeywordsLegionellosisPneumoniaResearch laboratories ePublished: 1 December 2008 Issue Published: 1 September 1978 PDF downloadLoading ...