Opiate and acetylcholine-independent analgesic actions of crotoxin isolated from crotalus durissus terrificus venom

Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib

Thomas J. Lynch, Daphne W. Bell, Raffaella Sordella et al. · New England Journal of Medicine · 2004 · 11.5K citations

Medicine, Oncology, Pharmacology +16

<i>EGFR</i> Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy

J. Guillermo Paez, Pasi A. Jänne, Jeffrey C. Lee et al. · Science · 2004 · 9.4K citations

Medicine, Molecular Genetics, Oncology +17

Systematic examination in the rat of brain sites sensitive to the direct application of morphine: Observation of differential effects within the periaqueductal gray

Tony L. Yaksh, Joseph C. Yeung, Thomas A. Rudy · Brain Research · 1976 · 606 citations

Medicine, Neuroscience, Pharmacology +17

Biological Roles of the Two Components of Crotoxin

R.A. Hendon, H. Fraenkel‐Conrat · Proceedings of the National Academy of Sciences · 1971 · 280 citations · Full text

Life Sciences, Biochemistry, Toxicology +16

Determination and characterization of the antinociceptive activity of intraventricularly administered acetylcholine in mice.

Norman W. Pedigo, William L. Dewey, Louis S. Harris · Journal of Pharmacology and Experimental Therapeutics · 1975 · 217 citations

Medicine, Pharmacology, Anesthesia +14