Transplantation · 1990 · 32 citations · 0 references
MedicineNephrologyPathologyKidney TransplantationUltrasonographyUltrasoundDoppler UltrasonographyKidney Transplant EvaluationRenal AssessmentRenal DiseaseRenal Function TestsTransplant RejectionAcute Rejection DetectionAcute Renal Allograft RejectionAllograft Biopsy DiagnosisBiopsy Diagnosis Of RejectionDoppler MeasurementsDuplex Ultrasound EvaluationRenal Transplant RejectionTransplant Rejection Assessment
Many studies have shown long-term benefits of HLA matching in kidney transplantation. By examining rates of graft loss within consecutive posttransplant intervals, using data from the UK Transplant Service, we show that the long-term benefits of HLA matching are due to reduction of the graft failure rate within five months of transplantation. After 5-months, HLA-A,B,DR matching appears to have little impact on graft loss. We suggest that graft losses after 5 months may be attributable to non-HLA targets.