Concepedia

The carcinogenic effect of aramite in rats.A study of hepatic nodules

Hans Pópper, Stephen S. Sternberg, Bernard L. Oser, Mona Oser

Cancer · 1960 · 77 citations · 10 references

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Concepts

Abstract

TOXICOLOGICAL studies of a commercial I miticide, Aramite, hepatocellular carcinomas were induced in a strain of rats receiving high oral doses.12 In subsequent investigations, large numbers of rats were kept for 2 years either on diets containing lower levels of Aramite or on basic control diets. In addition to instances of cancer, nodules consisting of liver or bile duct cells were found in the livers of both the control and the experimental animals.

References

10

Nodular regenerative hyperplasia of the liver.

Paul E. Steiner · PubMed · 1998 · 226 citations

, , +12

Progressive microscopic alterations in the livers of rats fed the hepatic carcinogens 3'-methyl-4-dimethylaminoazobenzene and 4'-fluoro-4-dimethylaminoazobenzene.

J. M. Price, John W. Harman, E. C. Miller et al. · PubMed · 1952 · 170 citations

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Pathologic Changes, With Special Reference to Pigmentation and Classification of Hepatic Tumors in Rats Fed <italic>p</italic>-Dimethylaminoazobenzene (Butter Yellow)<xref ref-type="fn" rid="fn1"><sup>1</sup></xref>

Jesse E. Edwards, Julius White · JNCI Journal of the National Cancer Institute · 1941 · 82 citations

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Histopathology of Carcinogenesis and Tumors of the Liver in Rats<xref ref-type="fn" rid="fn1">1</xref>

Harlan I. Firminger · JNCI Journal of the National Cancer Institute · 1955 · 73 citations

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Senile changes in the liver of mouse and man, with special reference to the similarity of the nuclear alterations

Warren Andrew, Harry Marshall Brown, James B. Johnson · American Journal of Anatomy · 1943 · 60 citations

, , +12