HTLV-1 envelope sequences from Brazil, the Caribbean, and Romania: Clustering of sequences according to geographic origin and variability in an antibody epitope

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.1K citations · Full text

Dna, Engineering, Dna Analysis +20

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

Randall K. Saiki, David H. Gelfand, Susanne Stoffel et al. · Science · 1988 · 17.1K citations

Engineering, Dna Analysis, Molecular Biology +19

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

Donald B. Smith, Kevin S. Johnson · Gene · 1988 · 6K citations

Protein Expression, Biochemistry, Single-step Purification +10

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

Bernard J. Poiesz, Francis W. Ruscetti, Adi F. Gazdar et al. · Proceedings of the National Academy of Sciences · 1980 · 5.1K citations · Full text

ANTIBODIES TO HUMAN T-LYMPHOTROPIC VIRUS TYPE-I IN PATIENTS WITH TROPICAL SPASTIC PARAPARESIS

Antoine Gessain, J C Vernant, L. Maurs et al. · The Lancet · 1985 · 2.8K citations

Vaccination, Diagnostic Virology, Viral Diagnostics +6