TRP-2 expression protects HEK cells from dopamine- and hydroquinone-induced toxicity

Oxidative Pathways for Catecholamines in the Genesis of Neuromelanin and Cytotoxic Quinones

Doyle G. Graham · Molecular Pharmacology · 1978 · 1.1K citations

Life Sciences, Biochemistry, Neurobiology +10

Crystal structure of a plant catechol oxidase containing a dicopper center

Thomas Klabunde, Christoph Eicken, James C. Sacchettini et al. · Nature Structural Biology · 1998 · 857 citations

Life Sciences, Biochemistry, Chemistry +11

A second tyrosinase‐related protein, TRP‐2, is a melanogenic enzyme termed DOPAchrome tautomerase.

Katsuhiko Tsukamoto, Ian J. Jackson, Kazunori Urabe et al. · The EMBO Journal · 1992 · 563 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +5

Glutathione transferases catalyse the detoxication of oxidized metabolites (o-quinones) of catecholamines and may serve as an antioxidant system preventing degenerative cellular processes

Sofia Baez, Juan Segura‐Aguilar, Mikael Widersten et al. · Biochemical Journal · 1997 · 340 citations · Full text

Life Sciences, Biochemistry, Neuroscience +15

A second tyrosinase‐related protein, TRP‐2, maps to and is mutated at the mouse slaty locus.

Ian J. Jackson, D. Chambers, Katsuhiko Tsukamoto et al. · The EMBO Journal · 1992 · 324 citations · Full text

Life Sciences, Genetics, Molecular Genetics +3