Concepedia

Effect of early interferon beta-1a therapy on conversion to multiple sclerosis in Iranian patients with a first demyelinating event

Hossein Pakdaman, Mohammad Ali Sahraian, A. Fallah, R. Pakdaman, Kourosh Ghareghozli, Elham Rahimian, Afsaneh Shirani

Acta Neurologica Scandinavica · 2007 · 14 citations · 10 references

DOI

Abstract

The results of our study, which are consistent with those from western studies, show that treatment at an early stage of MS delays conversion to definite MS and has positive effects on MRI outcomes.

References

10

Randomised double-blind placebo-controlled study of interferon β-1a in relapsing/remitting multiple sclerosis

George C. Ebers · The Lancet · 1998 · 2.1K citations

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Axonal damage in acute multiple sclerosis lesions

Betsy Ferguson · Brain · 1997 · 1.5K citations · Full text

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Intramuscular Interferon Beta-1A Therapy Initiated during a First Demyelinating Event in Multiple Sclerosis

Lawrence Jacobs, Roy W. Beck, Jack H. Simon et al. · New England Journal of Medicine · 2000 · 1.5K citations · Full text

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Effect of early interferon treatment on conversion to definite multiple sclerosis: a randomised study

Giancarlo Comi, Massimo Filippi, Frederik Barkhof et al. · The Lancet · 2001 · 1.1K citations

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Evidence of Axonal Damage in the Early Stages of Multiple Sclerosis and Its Relevance to Disability

Nicola De Stefano, Sridar Narayanan, Gordon Francis et al. · Archives of Neurology · 2001 · 505 citations · Full text