NF-κB: Ten Years After

Patrick A. Baeuerle, David Baltimore

Cell

InflammationAutoimmune DiseaseDisease MechanismImmunologyPathology +5

Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties

Peter Ertl, Bernhard Rohde, Paul M. Selzer

Journal of Medicinal Chemistry

EngineeringComputational ChemistryPolar FragmentsMolecular GraphicDrug Transport Properties +17

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

Joseph A. DiDonato, Makio Hayakawa, David M. Rothwarf, +2

Nature

InflammationCytokineTranscriptional RegulationSignal TransductionSignaling Pathway +9

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

Frank Mercurio, Hengyi Zhu, Brion W. Murray, +8

Science

ImmunologyMolecular BiologyInflammationSignaling PathwayCell Regulation +18

IκB Kinase-β: NF-κB Activation and Complex Formation with IκB Kinase-α and NIK

John Woronicz, Xiong Gao, Zhaodan Cao, +2

Science

Iκb Kinase-αImmunologyComplex FormationInflammationSignaling Pathway +17

Identification and Characterization of an IκB Kinase

Catherine H. Régnier, Ho Yeong Song, Xiong Gao, +3

Cell

Signal TransductionIκb KinaseSignaling PathwayCellular BiochemistryMedicine +5

Severe Liver Degeneration in Mice Lacking the IκB Kinase 2 Gene

Qiutang Li, Daniel Van Antwerp, Frank Mercurio, +2

Science

Severe Liver DegenerationApoptosisImmunologyCell DeathPathology +20

Abnormal Morphogenesis But Intact IKK Activation in Mice Lacking the IKKα Subunit of IκB Kinase

Yinling Hu, Véronique Baud, Mireille Delhase, +5

Science

Limb and Skin Abnormalities in Mice Lacking IKKα

Kiyoshi Takeda, Osamu Takeuchi, Tohru Tsujimura, +7

Science

Knockout MouseSkin DevelopmentDevelopmental BiologyMolecular PhysiologyAutoimmune Disease +13

IKK1-deficient mice exhibit abnormal development of skin and skeleton

Q. Li, Qin Lu, Ji Young Hwang, +4

Genes & Development