Concepedia

Nlrp3 is a key modulator of diet-induced nephropathy and renal cholesterol accumulation

Pieter J. Bakker, Loes M. Butter, Lotte Kors, Gwendoline J.D. Teske, Jan Aten, Fayyaz S. Sutterwala, Sandrine Florquin, Jaklien C. Leemans

Kidney International · 2013 · 97 citations · 49 references

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Concepts

References

49

The Inflammasome

Fabio Martinon, Kimberly Burns, Jürg Tschopp · Molecular Cell · 2002 · 6K citations · Full text

Gout-associated uric acid crystals activate the NALP3 inflammasome

Fabio Martinon, Virginie Pétrilli, Annick Mayor et al. · Nature · 2006 · 5.2K citations

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The Metabolic Syndrome and Total and Cardiovascular Disease Mortality in Middle-aged Men

Hanna‐Maaria Lakka · JAMA · 2002 · 5.1K citations

, , +17

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

Jay D. Horton, Joseph L. Goldstein, Michael S. Brown · Journal of Clinical Investigation · 2002 · 4K citations · Full text

, , +17

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Peter Duewell, Hajime Kono, Katey J. Rayner et al. · Nature · 2010 · 3.9K citations · Full text

, , +12