A heterozygous mutation (the codon for Ser447→ a stop codon) in lipoprotein lipase contributes to a defect in lipid interface recognition in a case with type I hyperlipidemia

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

Randall K. Saiki, David H. Gelfand, Susanne Stoffel et al. · Science · 1988 · 17.2K citations

Life Sciences, Biotechnology, Molecular Biology +12

A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells.

Hiroto Okayama, P Berg · Molecular and Cellular Biology · 1983 · 935 citations

Life Sciences, Molecular Biology, Molecular Genetics +15

Human growth hormone as a reporter gene in regulation studies employing transient gene expression.

Richard F. Selden, Kathleen Burke Howie, Mary Ellen Rowe et al. · Molecular and Cellular Biology · 1986 · 657 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Human Lipoprotein Lipase Complementary DNA Sequence

Karen L. Wion, Todd G. Kirchgessner, Aldons J. Lusis et al. · Science · 1987 · 481 citations

Life Sciences, Biochemistry, Molecular Biology +16

Detection and characterization of the heterozygote state for lipoprotein lipase deficiency.

Stephan P. Babirak, Per‐Henrik Iverius, W. Y. Fujimoto et al. · Arteriosclerosis An Official Journal of the American Heart Association Inc · 1989 · 294 citations · Full text

Life Sciences, Endocrinology, Enzymology +16