Clinical and Laboratory Characteristics of a Large Cohort of Symptomatic, Human Immunodeficiency Virus-infected Infants and Children

Abstract

These data provide a description of the clinical characteristics of HIV-infected US children at the time antiretroviral therapy is initiated for HIV-related symptoms. The high rate of abnormalities of growth, development and cognitive ability that were observed in children < 30 months of age demonstrates that treatment strategies should be developed for earlier intervention.