American Journal of Hospice and Palliative Medicine® · 2001 · 31 citations · 7 references
MedicinePharmacologyPharmacotherapyPain ManagementPain MedicinePsychopharmacologyAddictionAnalgesic PharmacologyDrugs Of AbuseOpioid AnalgesicsOpioid TherapyPharmacologic Pain TherapyCancer Pain ControlCancer Pain PharmacotherapyCancer-related Pain ControlMethadone Maintenance TherapyMethadone Maintenance TreatmentSide Effect Profile
Methadone is recommended as being free of some of the neuropsychological side effects noticed with morphine, which are attributed to active metabolites. A patient that received methadone for cancer-associated pain developed myoclonus as a side effect. This has rarely been reported before in the literature. The pathophysiology and management of myoclonus are discussed.
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The use of methadone in cancer pain poorly responsive to other opioids
J. S. Morley, Matthew Makin · Pain Reviews · 1998 · 131 citations
Dantrolene Treatment of Opioid-Induced Myoclonus
Sebastiano Mercadante · Anesthesia & Analgesia · 1995 · 29 citations
Medicine, Oncology, Pharmacotherapy +17