Medical Physics · 2000 · 69 citations · 8 references
Radiation ExposureReference ValuesRadiation ProtectionAbsorbed FractionsBiostatisticsRadiation Therapy PlanningPhoton-counting Computed TomographyRadiation OncologyInternal Dose EstimatesNuclear MedicineBiophysicsRadiologyHealth SciencesHuman BodyMedical ImagingRadiation TransportNeuroimagingVoxel‐based PhantomDosimetryBiomedical ImagingRadiation DoseMedicine
A new approach for calculating internal dose estimates was developed through the use of a more realistic computational model of the human body. The present technique shows the capability to build a patient-specific phantom with tomography data (a voxel-based phantom) for the simulation of radiation transport and energy deposition using Monte Carlo methods such as in the MCNP-4B code. MCNP-4B absorbed fractions for photons in the mathematical phantom of Snyder et al. agreed well with reference values. Results obtained through radiation transport simulation in the voxel-based phantom, in general, agreed well with reference values. Considerable discrepancies, however, were found in some cases due to two major causes: differences in the organ masses between the phantoms and the occurrence of organ overlap in the voxel-based phantom, which is not considered in the mathematical phantom.
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