Detection of ?-thalassemia and hemoglobin E genes in Thai by a DNA amplification technique

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

Randall K. Saiki, David H. Gelfand, Susanne Stoffel et al. · Science · 1988 · 17.2K citations

Life Sciences, Biotechnology, Molecular Biology +12

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

Randall K. Saiki, Stephen J. Scharf, Fred Faloona et al. · Science · 1985 · 9K citations

Medicine, Genetics, Molecular Genetics +17

Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes

Randall K. Saiki, Teodorica L. Bugawan, Glenn T. Horn et al. · Nature · 1986 · 1.8K citations

Life Sciences, Genetics, Molecular Genetics +14

Abnormal RNA processing due to the exon mutation of βE-globin gene

Stuart H. Orkin, Haig H. Kazazian, Stylianos E. Antonarakis et al. · Nature · 1982 · 307 citations

Life Sciences, Genetics, Molecular Genetics +10

Direct detection of haemoglobin E with MnlI.

Swee Lay Thein, Jodi Lynch, Julie M. Old et al. · Journal of Medical Genetics · 1987 · 23 citations · Full text

Medicine, Hematology, Biosensors +8