An efficient synthesis of (3R)-4-amino-3-hydroxy butyric acid (GABOB) via cyclic sulfite methodology

Systemic Carnitine Deficiency — A Treatable Inherited Lipid-Storage Disease Presenting as Reye's Syndrome

P Chapoy, C. Angelini, Wendy J. Brown et al. · New England Journal of Medicine · 1980 · 248 citations

Life Sciences, Biochemistry, Pharmacology +10

Total synthesis of (R)-glycerol acetonide and the antiepileptic and hypotensive drug (-)-.gamma.-amino-.beta.-hydroxybutyric acid (GABOB): use of vitamin C as a chiral starting material

Michael E. Jung, Teresa J. Shaw · Journal of the American Chemical Society · 1980 · 238 citations

Medicine, Medicinal Chemistry, Pharmacology +8

Chiral Compounds Synthesized by Biocatalytic Reductions [New Synthetic Methods (51)]

Helmut Simon, Johann Bader, Helmut Günther et al. · Angewandte Chemie International Edition in English · 1985 · 232 citations

Life Sciences, Biotechnology, Microbiology +15

Cyclic Sulfites and Cyclic Sulfates: Epoxide like Synthons

Braj B. Lohray · Synthesis · 1992 · 218 citations

Natural Sciences, Chemical Biology, Chemistry +17

Stereochemical control of yeast reductions. 5. Characterization of the oxidoreductases involved in the reduction of .beta.-keto esters

Woan-Ru Shieh, Aravamudan S. Gopalan, Charles J. Sih · Journal of the American Chemical Society · 1985 · 208 citations

Life Sciences, Biochemistry, Biocatalysis +12