Photodynamic and photohyperthermic response of malignant tumors

Abstract

This work presents an analytical dosimetry model for photodynamic therapy of malignant tumors. A hyperthermic contribution originating from the absorption of optical irradiation in the tissue may be equally taken into account. The model has been used to analyze tumor response during photodynamic therapy of an in vivo murine tumor. This tumor model was C3H/Tif mammary adenocarcinoma in C3D2F1/Bom mouse strain.