Acta Clinica Belgica · 2004 · 18 citations · 13 references
MedicineNephrologyPathologyGenitourinary RadiologyRenal Nuclear MedicineRenal PathologyGlomerular DiseasesGranulomatous InflammationRenal DiseaseRenal ImagingRenal ImmunopathologyRenal InflammationBiopsy Of Renal LesionsInfectious Renal Disease ImagingInflammatory Renal Disease ImagingKidney Biopsy FindingsKidney PathologyLeukocyte FunctionRenal Biopsy DiagnosisRenal Biopsy Findings
Malakoplakia is a rare inflammatory disease involving most frequently the urinary tract. We present a case of bilateral renal malakoplakia, in which FDG-PET contributed to diagnosis. We made this diagnosis on the basis of clinical presentation, renal biopsy showing a mixed cellular infiltrate with granuloma formation and possible Michaelis-Gutmann bodies, resolution of the lesions after prolonged antibiotic therapy and evidence of leukocyte dysfunction. We briefly discuss the pathophysiology and therapy of this rare and difficult to prove disease and the role of FDG-PET in the diagnosis of inflammatory and infectious diseases.
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