Journal of Applied Chemistry · 1956 · 55 citations · 1 references
Natural SciencesChemistryToxicologyBioorganic ChemistryMycologyOrganic ChemistryAntifungal AgentsFungal Secondary MetabolitesOrganic SynthesisNatural Antifungal CompoundsNew Antifungal AgentsStructure Elucidation Of Fungal MetabolitesTin Chemistry
Abstract The preparation of a number of unsymmetrical tri‐ n ‐alkyltin acetates is described. From the antifungal test results of these compounds it appears that a single rule governs the activity of both symmetrical and unsymmetrical tri‐ n ‐alkyltin acetates, namely that it is the total number of carbon atoms present in the alkyl groups, rather than the nature of the groups, which governs the fungitoxicity of the compounds; this is greatest for a total of 9–12 carbon atoms.
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