Science · 1961 · 183 citations · 9 references
MedicineBiochemistryPharmacologyNeurochemistryNeuropharmacologyPsychopharmacologyCholinergic NeurochemistryCholinergic PharmacologyMonoamine NeurochemistryNeurochemical PharmacologyPsychostimulant PharmacologySerotonergic PharmacologyDopamine BiosynthesisSerotonin BiosynthesisTryptophan Metabolism
An enzyme has been found that N-methylates serotonin and tryptamine to psychotomimetic metabolites, bufotenine and N,N-dimethyltryptamine. This enzyme is highly localized in the rabbit lung and also N-methylates phenylethylamine derivatives such as tyramine, phenylethylamine , mescaline, and dopamine.
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