MIy subject is one of very general interest.and also of considerable practical importance, if for no other reason than that a large number of our patients at or over middle age present a raised blood pressure. No one can now afford to be indifferent to the problems associated with -variations in blood pressure, for a high pressure is an 'abnormality which always demands investigation, super--vision, and careful treatment. There is a danger that patients may take the variations in their blood pressure too seriously, and it is well to remember that the blood pressure is only one factor in-the circulation, and that it must be carefully correlated with the other physical signs and symptoms manifested.