Concepedia

PTK787/ZK22258 attenuates stellate cell activation and hepatic fibrosis in vivo by inhibiting VEGF signaling

Yuqing Liu, Eric Lik Hang Lui, Scott L. Friedman, Lei Li, Tao Ye, Yongjun Chen, Ronnie T.P. Poon, Jana Y. Wo, Tsz Wai Kok, Sheung Tat Fan

Laboratory Investigation · 2008 · 37 citations · 30 references

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References

30

Liver fibrosis

Ramón Bataller · Journal of Clinical Investigation · 2005 · 1.5K citations · Full text

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Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors.

John P. Iredale, R. Christopher Benyon, J. Pickering et al. · Journal of Clinical Investigation · 1998 · 1.1K citations · Full text

, , +17

Hepatic lipocytes: the principal collagen-producing cells of normal rat liver.

Scott L. Friedman, F J Roll, J K Boyles et al. · Proceedings of the National Academy of Sciences · 1985 · 865 citations · Full text

, , +14

Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing.

N. Nissen, Peter J. Polverini, Alisa E. Koch et al. · PubMed · 1998 · 840 citations

, , +12

Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis

Christophe Corpechot, Véronique Barbu, Dominique Wendum et al. · Hepatology · 2002 · 474 citations

, , +16