The Human Aldose Reductase AKR1B1 Qualifies as the Primary Prostaglandin F Synthase in the Endometrium

Eva Bresson, Sofia Boucher-Kovalik, Pierre Chapdelaine, Éric Madore, Nathalie Harvey, Philippe Y. Laberge, Michel A. Fortier

The Journal of Clinical Endocrinology & Metabolism · 2010 · 62 citations · 30 references

DOIFull text

Open access

Abstract

The human aldose reductase AKR1B1 currently associated with diabetes complications is also a highly functional PGF synthase responsible for PGF2α production in the human endometrium and a potential target for treatment of menstrual disorders.

References

30