Development of an oral sustained release drug delivery system utilizing pH-dependent swelling of carboxyvinyl polymer

Transit of pharmaceutical dosage forms through the small intestine.

S.S. Davis, John G. Hardy, J W Fara · Gut · 1986 · 848 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Determination of morphine, morphine-3-glucuronide and (tentatively) morphine-6-glucuronide in plasma and urine using ion-pair high-performance liquid chromatography

Jan‐Olof Svensson, Anders Rane, Juliette Säwe et al. · Journal of Chromatography B Biomedical Sciences and Applications · 1982 · 278 citations

Pharmacy, Pharmacokinetics, Pharmacology +11

Intestinal transit of bioadhesive microspheres in an in situ loop in the rat—A comparative study with copolymers and blends based on poly(acrylic acid)

Claus‐Michael Lehr, Johanna A. Bouwstra, Josef J. Tukker et al. · Journal of Controlled Release · 1990 · 185 citations

Pharmacy, Bioengineering, Biomedical Engineering +15

A novel pH- and time-based multi-unit potential colonic drug delivery system. I. Development

Vishal Gupta, Thomas E. Beckert, James C. Price · International Journal of Pharmaceutics · 2001 · 161 citations

Pharmacy, Pharmaceutics, Pharmacology +8

In Vitro and in Vivo Evaluation of Mucoadhesive Microspheres Prepared for the Gastrointestinal Tract Using Polyglycerol Esters of Fatty Acids and a Poly(acrylic acid) Derivative

Yohko Akiyama, Naoki Nagahara, Toshio Kashihara et al. · Pharmaceutical Research · 1995 · 131 citations

Pharmacy, Pharmaceutics, Drug Delivery +16