Skewed Expression of the Genes Encoding Epigenetic Modifiers in High-Risk Uveal Melanoma - Concepedia

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Publication | Open Access

Skewed Expression of the Genes Encoding Epigenetic Modifiers in High-Risk Uveal Melanoma

DOI Full Paper Access

41

Citations

51

References

2015

Year

Nola S. Herlihy, Mehmet Doğrusöz, T. Huibertus van Essen, J. William Harbour, Pieter A. van der Velden, Marja C.J.A. van Eggermond, Geert W. Haasnoot, Peter J. van den Elsen, Martine J. Jager

Investigative Ophthalmology & Visual Science

Abstract

Expression levels of a number of histone-modifying genes and polycomb family members are significantly lower in uveal melanoma with monosomy 3/class 2, supporting a general dysregulation of epigenetic modifiers in UM with a bad prognosis.

References

	Year	Citations

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