Distinct Chromosomal Imbalances in Nonpolypoid and Polypoid Colorectal Adenomas Indicate Different Genetic Pathways in the Development of Colorectal Neoplasms

Kisten ras mutations in patients with colorectal cancer: the “RASCAL II” study.

David Cunningham, J. Oates, Joanne Young et al. · IRIS UNIMORE (University of Modena and Reggio Emilia) · 2001 · 890 citations · Full text

Medicine, Genetics, Oncology +12

Mutations in APC, Kirsten-ras, and p53—alternative genetic pathways to colorectal cancer

Gillian Smith, Francis A. Carey, Julie Beattie et al. · Proceedings of the National Academy of Sciences · 2002 · 522 citations

Medicine, Genetics, Oncology +17

Comparative genomic hybridization, loss of heterozygosity, and DNA sequence analysis of single cells

Christoph A. Klein, Oleg Schmidt‐Kittler, Julian Schardt et al. · Proceedings of the National Academy of Sciences · 1999 · 455 citations

Life Sciences, Cell Biology, Genetics +17

Small “flat adenoma” of the large bowel with special reference to its clinicopathologic features

Tetsuichiro Muto, J Kamiya, T. Sawada et al. · Diseases of the Colon & Rectum · 1985 · 425 citations

Medicine, Oncology, Pathology +16

Comparative genomic hybridization reveals a specific pattern of chromosomal gains and losses during the genesis of colorectal tumors

Thomas Ried, Regina Knutzen, Rüdiger G. Steinbeck et al. · Genes Chromosomes and Cancer · 1996 · 392 citations

Medicine, Genetics, Oncology +14