Conjunctival Impression Cytology, Ocular Surface, and Tear-Film Changes in Patients Treated With Systemic Isotretinoin

Abstract

Conjunctival epithelial cells, tear basal secretion, and tear quality are markedly affected in patients during systemic treatment with isotretinoin (0.8 mg/kg). Ocular adverse effects of isotretinoin are generally not serious and are reversible after discontinuation.