Archives of Internal Medicine · 1984 · 292 citations · 10 references
MedicineInternal MedicinePulmonary Function TestingPulmonologyChronic Obstructive Pulmonary DiseaseHealth-related Quality Of LifeHealth-related Quality Of Life MeasurementQuality Of LifeQuality Of Life AssessmentRespiratory DiseaseChronic Obstructive Pulmonary Disease PathophysiologyLong-term Quality Of LifeQuality Of Life ImpairmentQuality Of Life PredictionRespiratory Status Assessment
Measures of quality of life were obtained from 985 mildly hypoxemic COPD patients, and a subsample of 100 received extensive neuropsychological and personality testing. Mildly hypoxemic COPD patients showed impaired quality‑of‑life activities, with relatively preserved physical function but comparable psychosocial impairment; tension‑anxiety was the strongest predictor of both physical and psychosocial QoL, while exercise capacity, FEV1, and neuropsychological status predicted physical limitations but not psychosocial functioning, and PaO2 was unrelated to QoL. Arch Intern Med 1984;144:1613‑1619.
• Measures of quality of life were obtained on 985 patients with mild hypoxemia and chronic obstructive pulmonary disease (COPD). A subsample of 100 patients were also given extensive neuropsychological and personality tests. Mildly hypoxemic COPD patients showed impairment in quality-of-life activities. They showed less impairment in physical function, compared with previous studies on COPD patients with hypoxemia, but about equal impairment in psychosocial function and dysphoric mood. Nonrelated health changes in life do not seem to account for these findings. Degree of self-reported tension-anxiety was the single greatest predictor of both physical and psychosocial measures of quality of life. Level of exercise completed, forced expiratory volume in 1 s, and neuropsychological status were significantly related to physical limitations, but not psychosocial functioning. The Pao2 was not significantly related to quality-of-life measures in this patient group. (<i>Arch Intern Med</i>1984;144:1613-1619)
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